A new UN publication highlights the importance of sustainable wastewater (WW) treatment for a healthy planet. One of the main classes of emerging pollutants in the WW are pharmaceuticals. The reuse or environmental release of insufficiently treated WW increases the risk of pharmaceutical pollution, undermining human and ecosystem health. Advanced WW treatment techniques can only partially remove pharmaceuticals. Within the circular economy, using WW as a valued resource, this report calls for action with several proposals, such as source separation, e.g., using urine-diverting toilets as urine accounts for only 1% of the domestic WW, while containing 64% of the pharmaceuticals in WW.